«Each era has its own view»

Each rhodopsin molecule binds its own arrestin.

Arrestins (Arrs) are ubiquitous regulators of the most numerous family of signaling proteins, G protein-coupled receptors. Two models of the Arr-receptor interaction have been proposed: the binding of one Arr to an individual receptor or to two receptors in a dimer. To determine the binding stoichiometry in vivo, we used rod photoreceptors where rhodopsin (Rh) and Arr are expressed at comparabl...

Motif) to Each (mhc Molecule) Its Own (binding

An Inventory of Taste in Caterpillars: Each Species Its Own Key*

Food plant recognition in lepidopterous larvae is predominantly governed by the activity of eight taste neurones present in two sensilla styloconica located on each maxilla. This paper reviews the results of electrophysiological and behavioural studies made on various caterpillar species during the last 40 years. It appears that all species, even closely related ones, have different taste syste...

POINT OF VIEW Has empowerment lost its power?

Empowerment is espoused as a flagship value of health promotion. From the bold assertions in the Ottawa Charter [1] and the Jakarta declaration [2] through to the recent commitment in Nairobi [3], the discourse of empowerment has been unwavering throughout. This short points of view paper intends to stimulate critical discussion about the continued value and use of empowerment in contemporary h...

Spectral effect: each population must have its own normal midnight salivary cortisol reference values determined

INTRODUCTION The mesurement of midnight salivary cortisol provides the most sensitive method for screening of Cushing's sendrome. However the clinical significance of spectral error is the requirement for determination of normal reference values in each population for each test, which will be used as the diagnostic method. Salivary cortisol levels may be affected by individual factors such as n...